The
Investigation
of
Events
that
followed
the
death
of
Cyril
Mark
Isaacs
ISAAC
REPORT
-
CONTENTS
Foreword
Main
conclusions
Unanswered
questions
about
the
joint
programme
Recommendations
Section
1 What
happened
after
Mr
Isaacs'
death
Ch
1 The
death
of
Cyril
Mark
Isaacs
Ch
2 Investigation
of
Mr
Isaacs'
death,
the
inquest
and
its
aftermath
Ch
3 Investigation
of
the
post
mortem
examination
of
Mr
Isaacs
at
Prestwich
mortuary
Ch
4 Were
other
organs
of
Mr
Isaacs
retained
for
use
at
Manchester
University?
Section
2 Research
on
brains
retained
at
post
mortem
Ch
5 The
legal
framework:
guidance
to
the
NHS
on
organ
retention
and
the
collection
of
pituitary
glands,
and
Home
Office
advice
to
Coroners
Ch
6 Ethics
Committees
and
access
to
health
records
for
post
mortem
research
Ch
7 The
retention
of
brains
after
post
mortem
and
the
origins
of
brain
research
and
brain
banks
Ch
8 The
Cerebral
Function
Unit
and
the
Neuro
Special
Pathology
Collection
at
Manchester
University
Section
3 The
research
programme
of
the
Departments
of
Physiology
and
Psychiatry
of
Manchester
University
(the
'Joint
Programme')
Ch
9 Origin
of
the
joint
programme,
funding
application
to
the
North
West
Regional
Health
Authority
and
progress
1985-1988
Ch
10 Brain
collection
at
Prestwich
mortuary
1985-1989
and
arrangements
with
the
Coroner's
office
Ch
11
Development
of
the
joint
programme
at
Manchester
University
from
1988:
applications
for
research
funds
and
awards
Ch
12 Prestwich
mortuary.
Application
to
the
Salford
Ethics
Committee,
January
1986
Ch
13
North
Manchester
General
Hospital
mortuary.
Application
to
the
North
Manchester
Ethics
Committee
Ch
14
Action
to
enlarge
the
programme
and
increase
the
collection
of
brains
from
other
hospitals:
approaches
to
consultants
and
Ethics
Committees
Ch
15 Warrington
General
Hospital.
Application
to
Warrington
Hospital
Ethics
Committee
Ch
16
Analysis
of
brains
collected
for
the
brain
bank
of
the
joint
research
programme
1985-1997
Ch
17 What
happened
to
the
brains
obtained
for
the
joint
programme?
Ch
18 Approval
of
the
joint
programme
by
Ethics
Committees
and
letters
to
general
practitioners
of
'control'
cases
Ch
19 Pathology
reports
submitted
to
Coroners
in
Manchester
and
Cheshire
Ch
20 Access
to
medical
records
Ch
21 Who
was
aware
of
the
role
of
the
North
Manchester
Coroner's
office
in
identifying
suitable
brains
for
the
joint
programme?
Ch
22
Was
the
retention
of
brains
known
to
Coroners
in
Manchester
and
Cheshire?
Ch
23 Consent
from
relatives
for
brain
retention
Ch
24 Other
features
of
the
joint
programme
Ch
25 Why
were
brains
from
Coroners'
post
mortems
retained?
Unanswered
questions
about
the
joint
programme
Section
4 Research
at
other
locations
on
brains
from
Coroners'
cases
Ch
26 The
Cambridge
brain
bank
Ch
27 The
death
of
David
Webb
Ch
28 Queen's
Medical
Centre,
Nottingham
Ch
29 The
death
of
Stuart
Fayle
Ch
30 The
Radcliffe
Infirmary,
Oxford
Ch
31 Brain
collections
used
for
research
under
Coroners
Rules
9
and
12
Ch
32 Centres
that
carried
out
research
under
Coroners
Rules
9
and
12
Ch
33 The
Corsellis
collection
Ch
34 Questionnaire
to
NHS
Trusts
Ch
35 The
importance
of
openness
where
brains
from
Coroners'
cases
are
retained
for
diagnostic
purposes
Section
5
The
collection
and
use
of
brains
for
teaching
Ch
36 The
retention
of
brains
for
teaching
Section
6 Brain
retention
and
the
Special
Hospitals
Ch
37 Brain
retention
from
post
mortems
after
death
in
the
Special
Hospitals
Section
7 Research
funding
organisations
and
Royal
Colleges
Ch
38 The
Medical
Research
Council
and
post
mortem
brain
banks
for
research
Ch
39 The
Wellcome
Trust:
funding
of
brain
research
Ch
40 The
Royal
College
of
Pathologists:
guidance
Ch
41 The
Royal
College
of
Psychiatrists:
guidance
Section
8 Approaches
to
post
mortems
and
organ
retention
Ch
42 Pathologists
and
post
mortem
reports
Ch
43 The
different
purposes
of
Coroners'
and
hospital
post
mortems
Ch
44 Legislation
on
the
use
of
bodies,
organs
and
tissues;
Coroners'
post
mortems;
procedures
and
alternatives
Ch
45 Views
of
relatives
and
religious
faiths
on
post
mortems
and
organ
retention
Section
9
The
importance
of
post
mortem
research
to
the
future
of
Health
Care
Ch
46 The
benefits
of
post
mortem
research:
clinical
and
ethical
aspects
of
the
retention
of
organs
and
tissues
Section
10
What
has
already
changed
and
further
changes
that
are
needed
Ch
47 Changes
to
procedures
of
Coroners'
post
mortems
to
prevent
unauthorised
brain
retention
Summary
Annexes
Appendices
Acronyms
Glossary
|
