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The Investigation of Events that followed the death of Cyril Mark Isaacs
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Glossary of Terms

Alzheimer's Disease

A progressive form of dementia occurring usually in late middle age. It is associated with diffuse degeneration disease of the brain.

Autopsy

Examination of a body after death in order to determine the cause of death or presence of disease processes. (Also referred to as post mortem examination or necropsy).

Community or Public Mortuary

A mortuary owned by the local authority with facilities for the storage and preservation of material and for the conduct of post mortems on persons who have died in the community.

Controls (as applied to pathology)

Specimens of organs or tissues obtained from individuals who are not affected by the disease process that is being investigated. These 'normal' control organs or tissues can be compared with those obtained from those individuals possibly affected by the disease process that is being investigated.

Coroner

An independent judicial officer acting on behalf of the Crown to investigate the cause and circumstances of violent or unnatural deaths, or sudden deaths of an unknown cause. Coroners must be legally and/or medically qualified, although most are now drawn from the legal profession.

Coroner's Officer

A Coroner's Officer is either a serving police officer permanently seconded to the Coroner's office to undertake the day-to-day routine of investigation of deaths reported to the Coroner, or a civilian appointed for the same purpose. The Coroner's Officer's duties may entail the Officer compiling a report in respect of each sudden death. She/he may compile the report her/himself or collate reports provided by uniformed police officers and other witnesses. Increasingly the position of Coroner's Officer has been made a civilian rather than a police appointment.

Coroner's Post Mortem

Post mortem examination carried out on the instructions of the Coroner. The consent of the next of kin is not required for a Coroner's post mortem. The purpose of a Coroner's post mortem examination is to provide the Coroner with information relevant to determining the cause of death. The Coroner is not required to order a post mortem examination in every case reported to him where information obtained from other sources provides satisfactory evidence to establish the cause of death.

Coroners Rules 1984

The Rules set out in secondary legislation the procedures that Coroners should observe in the exercise of their duties. The present Rules, enacted by Parliament, became operative on 1 July 1984. The Rules set out procedures to be followed in arranging post mortem examinations, burial orders, inquests, records to be kept and documents and forms to be used.

Coroner's Staff

The administrative office staff employed by the local authority to assist the Coroner in carrying out his duties.

Dementia

A disorder of brain function, usually chronic and progressive, that is the result of brain disease but may follow severe head injuries. Dementia is characterised by memory loss, particularly short-term loss, changes in personality, inability to attend to personal care, confusion and disorientation.

Down's Syndrome

A congenital disorder that is the single most frequent cause of mental retardation. It is the result of the affected person usually having 47 chromosomes rather than the usual 46. Down's Syndrome is characterised by learning difficulties of varying severity and sometimes physical abnormalities.

Ethics Committee (EC)

A committee set up to advise NHS bodies (or other organisation) on the ethical acceptability of research proposals involving human subjects or human material. Ethics Committees provide independent advice and members of the committees include in their membership both lay and professional members who bring together a broad range of experience and expertise to reconcile scientific and medical aspects of research with the interests and welfare of research subjects.

Histology

The study of the internal structure of cells and tissues by means of special staining techniques combined with light and electron microscopy.

Hospital Mortuary

A mortuary on a hospital site with facilities for the storage of bodies of those who have died in the hospital and usually for the conduct of post mortems.

Huntington's Disease

A progressive hereditary disease characterised by involuntary movements and dementia. The genetic defect has now been identified and genetic screening is available for those at risk.

Inquest

A public hearing called by the Coroner in specific circumstances to ascertain the identity of the deceased and to establish how, when and where the death occurred. The proceedings are inquisitorial by nature. An inquest is appropriate when the person:

  • died a violent or unnatural death; or
  • died a sudden death of which the cause is unknown; or
  • died in prison or in such a place or in such circumstances as to require an inquest under any other Act.

    Jewish Burial Board

    A co-operative organisation within a Jewish community that makes arrangements for funerals and pays burial costs and fees for its members.

    Magnetic Resonance Imaging (MRI)

    A non-invasive method of imaging the body and organs within it. The technique has been used in some locations with the agreement of the Coroner to identify the cause of death as an alternative to post mortem. However, the technique is applicable for this purpose in a minority of cases of sudden death and requires further evaluation.

    Mortuary Technician

    An employee of the hospital or local authority who is responsible for the operation of the mortuary in respect of the reception and storage of bodies. Where a post mortem is undertaken, the technician assists and is directed by the pathologist during the examination.

    Neuropathology

    A study of diseases affecting the nervous system by microscopic examination of tissue samples to identify diseases and injuries to the brain and spinal cord.

    Organ

    A part of the body that forms a structural unit and/or is responsible for a particular function (or functions). Organs may be composed of more than one tissue and may be large, for example the liver, or very small, for example the pituitary.

    Parkinson's Disease

    A disorder predominantly of middle aged and elderly people characterised by tremor, rigidity, mask-like facial immobility and a poverty of spontaneous movement. The first and most prominent symptom is tremor, which often initially affects one limb and then spreads progressively to affect other limbs.

    Schizophrenia

    A mental disorder (or group of disorders) of variable severity characterised by a disintegration of the process of thinking, of contact with reality, and of emotional responsiveness and usually extensive withdrawal of an individual's interest in other people and their outside world. Delusions and hallucinations (especially hearing voices) are frequent features, and a patient with this disorder often feels that their thoughts, sensations, and actions are controlled by, or shared with, others.

    Tissue

    A collection of cells specialised to perform a particular function. The cells may be of the same type (e.g. in nervous tissue) or of different types (e.g. in connective tissue). Aggregations of tissue constitute organs.

    Tissue Blocks

    Tissue blocks are small samples taken from organs which are then stabilised by a process called 'fixation' so that wafer thin slices may later be cut for examination on glass slides under the microscope.

    Toxicology

    The study of poisonous materials and their effects upon living organisms. Toxicological investigations may form part of a post mortem examination to discover if drugs, or other chemical substances, were implicated or caused death.


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